Download A Jew Among Romans: The Life and Legacy of Flavius Josephus by Frederic Raphael PDF

By Frederic Raphael

From the acclaimed biographer, screenwriter, and novelist Frederic Raphael, here's an audacious background of Josephus (37–c.100), the Jewish common became Roman historian, whose emblematic betrayal is a touchstone for the Jew by myself within the Gentile world.
Joseph ben Mattathias’s transformation into Titus Flavius Josephus, historian to the Roman emperor Vespasian, is a gripping and dramatic tale. His lifestyles, within the arms of Frederic Raphael, turns into some degree of departure for an appraisal of Diasporan Jews looking a spot within the dominant cultures they inhabit. Raphael brings a scholar’s rigor, a historian’s standpoint, and a novelist’s mind's eye to this venture. He is going past the attention-grabbing info of Josephus’s lifestyles and his singular literary achievements to envision how Josephus has been seen via posterity, discovering in him the prototype for the un-Jewish Jew, the assimilated highbrow, and the abiding apostate: the recurrent figures within the lengthy centuries of the Diaspora. Raphael’s insightful pics of  Yehuda Halevi, Baruch Spinoza, Karl Kraus, Benjamin Disraeli, Ludwig Wittgenstein, and Hannah Arendt expand and light up the Josephean worldview Raphael so eloquently lays out.

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Similarly, the Cochrane review of sulfasalazine in AS did not identify any clinically meaningful benefit (Chen, 2014). While in clinical practice sulfasalazine may be tried for peripheral joint involvement in clinical practice, most axSpA patients with Peripheral musculoskeletal involvement significant disease will ultimately require treatment with TNF inhibitors, which have been shown to be effective for peripheral arthritis in axSpA. Hips Hip involvement in axSpA is generally a bad prognostic feature and can have a devastating effect on patients’ function and quality of life.

In response to treatment with TNF inhibitors), the brake is released, allowing tissue repair and new bone formation to occur. As a result of this uncoupling between inflammation and new bone formation, patients who otherwise respond well to anti-​TNF therapy may appear to have radiographic progression due to the new bone formation (which would have occurred in many anyway, but at a later date, in the absence of TNF inhibition). Additional research is needed to confirm whether progression is due to persistent, low-​grade inflammation or to the release of the TNF brake once inflammation is effectively treated, but there is 31 32 A x i al S p o n d y l o a r t h r i t i s accumulating data to suggest that when patients are followed up for longer, treatment with TNF blockers results in slowing of radiographic progression, supporting the latter mechanism.

2014;66(2):231–​41. 38291. 35 Chapter 6 Inflammatory back pain Key points • Inflammatory back pain (IBP) refers to a collection of symptoms that help identify patients with possible inflammatory spinal disease. • Symptoms suggestive of IBP include: onset of symptoms aged <40 years, improvement with exercise, worsening with rest, early morning stiffness lasting >30 minutes, and improvement with NSAIDs. • IBP criteria were initially developed and validated in patients with ankylosing spondylitis, but have subsequently been shown to perform similarly in patients with axial spondyloarthritis (axSpA).

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