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By James L Bittle; Frederick A Murphy

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Additional resources for Advances in veterinary science and comparative medicine. Vol. 33, Vaccine biotechnology

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2. Campylobacter fetus intestinalis Unlike C. fetus venerealis, this bacterium is contracted by ingestion and is not transmitted venereally. Both sheep and cattle can be infected; however, the disease is most severe in pregnant ewes, which undergo a high percentage of abortions or premature births within a flock. Immunization. In sheep, vaccination with polyvalent adjuvanted vaccines is efficacious in preventing disease (Thompson and Gilmour, 1978). G. Vibrio The most important organism of this genus, V.

Escherichia coli Enterotoxigenic pathogenic strains of Escherichia coli may cause severe, potentially fatal, diarrheal disease in both man and domestic species, particularly neonatal cattle and swine. The capsular (K) antigens are cell-surface proteins and/or polysaccharides associated with virulence. , 1979). Escherichia coli neonatal enteritis of newborn calves is also a serotype-specific disease (Myers 44 J A M E S L. BITTLE A N D S U S I E M U I R and Guinée, 1976). Ail important colostral antibodies in both swine and cattle are anti-K antibodies (usually K99) (Myers and Guinée, 1976; Moon et ah, 1978).

Leptospires are transmitted through contact with the urine of animal carriers, either directly or in contaminated water or soil. Rodents are the primary reservoir of the bacteria which, due to its ability to synthesize urease, colonizes the renal nephron and subsequently is shed into the urine. Leptospirosis causes economically serious disease in cattle and swine by causing fetal death, abortion, and infertility. Recovery from infection with one serotype lends immunity only to that serotype. , 1971).

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